Non sedating anti emetic
For oral administration the dosage will be up to 10 mg per day, preferably up to 8 mg per day in single or divided doses. The present invention furthermore includes within its scope a method for the treatment of nausea and/or vomiting, which method comprises the administration to a patient of methotripremazine in a non-sedating amount.The category is separated by medications that cause sedation or not.Dopiminergic Best treated at the initiation of opioid therapy.Also, nausea and vomiting during a migraine attack can seriously interfere with the effectiveness of oral medications.Oral medications are a good choice for people who have tension-type headache, migraine without nausea and vomiting, or migraine attacks that come on slowly, allowing early treatment.ANTI-EMETIC PHARMACEUTICAL COMPOSITIONS CONTAINING METHOTRIMEPRAZINE The present invention relates to anti-emetic pharmaceutical compositions and, in particular, to anti-emetic pharmaceutical compositions which contain methotrimeprazine.
Phenergan (promethazine) is a pretty good medication for symptomatic treatment of nausea. If you are still symptomatic with those medications, you should be seen and evaluated by your physician to find out what causes it. Many otc sleep meds contain Diphenhydramine (benadryl). Read more Flixonase or Flonase (fluticasone proprionate) is a steroid nasal spray commonly used to treat allergic rhinitis by decreasing the allergic inflammation in the nasal mucosa. While some people find temporary relief for insect bites with this, in general it is not very effective compared to other antihistamines taken as pills or tabs.
Drugs taken in the form of pills and capsules are absorbed through the gastrointestinal tract.
Sublingual tablets or lozenges that are held under the tongue to dissolve are another approach.
Methotrimeprazine, in doses between 2.5 mg and 12.5 mg per 24 hours (mean 5 mg), was administered by continuous subcutaneous (s.c.) infusion (via syringe driver) in a total of 23 patients with one or more of the following, presumptive, causes of nausea and vomiting: a) drug induced, principally unresponsive to oral and/or s.c. b) metabolic, principally unresponsive to oral and/or s.c.
The majority of patients had previously failed to respond to oral cyclizine, metoclopramide and/or prochlorperazine. Only one of the 23 patients (given 12.5 mg per 24 hours) experienced sedation to any degree.